The genome of non-O1 Vibrio cholerae NRT36S demonstrates the presence of pathogenic mechanisms that are distinct from those of O1 Vibrio cholerae.

نویسندگان

  • Yuansha Chen
  • Judith A Johnson
  • Gordon D Pusch
  • J Glenn Morris
  • O Colin Stine
چکیده

Vibrio cholerae NRT36S is a non-cholera toxin-producing, non-O1 strain that causes diarrhea in volunteers. The genome of NRT36S was sequenced to create a draft containing 174 contigs plus the superintegron region. Our analysis of the draft genome revealed several putative toxin genes and colonization factors. Besides confirming the existence of nonagglutinable heat-stable toxin, we also identified the genes for a type three secretion system, a putative exotoxin, two different RTX toxins, and four pilus systems.

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عنوان ژورنال:
  • Infection and immunity

دوره 75 5  شماره 

صفحات  -

تاریخ انتشار 2007